目录号 | 产品详情 | 靶点 | |
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T80049 | Sodium Channel | ||
μ-Conotoxin GIIIB为含22个氨基酸残基的多肽,源自鱼食性圆锥蜗牛Conus geographus的毒液。该化合物作用于NaV1.4通道,具有抑制功能,能够阻止肌肉细胞收缩。 | |||
T83943 | |||
ING-2 AM是一种能透过细胞膜的荧光钠离子(Na+)指示剂,与钠结合(Kd=20 mM)。激发和发射峰值(λ)分别为525 nm和545 nm。该化合物对K+离子具有20倍的选择性。在体外和原位实验中用于检测实时的钠流入。 | |||
T70975 | |||
Carsatrin succinate is the salt form of Carsatin, a purinylpiperazine derivative used as a cardiotonic and antiarrhythmic. Carsatrin acts as positive inotropic agent that increases twitch tension and prolongs the action potential (AP) duration of ventricular muscle without affecting the Na+, K+-ATPase, adenylyl cyclase, phosphodiesterase isozymes, or cardiac myofilaments. Carsatrin’s positive inotropic effect can be prevented by tetrodotoxin but not by the adrenergic antagonists timolol, yohimbine, or prazosin. | |||
T80496 | Calcium Channel | ||
Kurtoxin是一种选择性Cav3 (T-type) 电压门控Ca2+通道抑制剂,对Cav3.1 (α1G T-type) Ca2+通道的Kd值为15 nM。该化合物与中枢和外周神经元的L型、N型和P型Ca2+通道有高度亲和性,并对电压门控Na+通道也有交叉反应性。 | |||
T36980 | |||
Histone H3K27Me1 (23-34) is a peptide fragment of histone H3 that corresponds to amino acid residues 24-35 of the human histone H3.1 and H3.2 sequences. Monomethylation of histone H3 at lysine 27 is associated with actively transcribed genes and positively correlates with H3K36 trimethylation. Levels of H3K27Me1 are increased in tumor tissue isolated from patients with metastatic hormone-na ve and castration-resistant prostate cancer. Histone H3K27Me1 (23-34) has been used in epitope mapping of the lupus-derived monoclonal antibody BT164. | |||
T24692 | |||
QAQ dichloride is a photoswitchable compound that blocks voltage-gated Na v and K v channels. Its channel-blocking activity is observed in the trans form of the azobenzene photoswitch, while the cis form does not exhibit this effect. This compound is membrane-impermeant and selectively enters pain-sensing neurons expressing endogenous import channels. QAQ dichloride functions as a light-sensitive analgesic and provides a valuable tool for investigating signaling mechanisms involved in acute and chronic pain [1] [2]. | |||
T38151 | |||
Germicidin A is a pyranone originally derived from S. viridochromogenes that acts as a reversible, autoregulative inhibitor of spore germination and hyphal elongation in the genus Streptomyces at concentrations as low as 200 pM. During germination, spores of Streptomyces excrete germicidin A along with other germicidin homologs, which inhibit germination of its own arthrospores. At higher concentrations, germicidin A can inhibit the porcine Na+/K+-activated ATPase (ID50 = 100 μM) and prevent the germination of the cress L. sativum. | |||
T70428 | |||
Nepaprazole Na is the salt form of Nepaprazole Free Base, also known as TY-11345, is a proton pump inhibitor potentially for treatment of gastric ulcer. TY-11345 potently inhibited H+/K(+)-ATPase activity in isolated rabbit gastric mucosal microsomes; and the inhibitory effect was enhanced under weak acid conditions, the IC50 (concentrations that inhibit the enzyme activity by 50%) being 5.8 microM and 9.9 microM at pH 6.0 and pH 7.4, respectively. TY-11345 should be useful for the clinical treatment of peptic ulcer diseases. | |||
T68808 | |||
11-Dehydrocorticosterone is an endogenous mineralocorticoid. It increases Na+/K+-ATPase mRNA expression in vascular smooth muscle cells and inhibits aldosterone action in B. marinus toad bladder tissue in a concentration-dependent manner. 11-Dehydrocorticosterone decreases the sodium/creatine ratio and increases the potassium/creatine ratio in rat urine in a dose-dependent manner in a model of 11β-hydroxysteroid dehydrogenase inhibition induced by carbenoxolone. Chronic administration 11-dehydrocorticosterone increases plasma glucocorticoids levels, body weight gain, and adiposity, as well as induces insulin resistance in mice. | |||
T38069 | |||
Aquastatin A is a fungal metabolite originally isolated fromF. aquaeductuumthat has diverse biological activities.1It is active againstS. aureus(MIC = 32 μg/ml) and inhibits enoyl-acyl carrier protein reductase (Fabl; IC50= 3.2 μM) andS. aureusfatty acid synthesis (IC50= 3.5 μM).2Aquastatin A also inhibits the Na+/K+-ATPase and H+/K+-ATPase (IC50s = 7.1 and 6.2 μM, respectively), as well as protein tyrosine phosphatase 1B (PTP1B; IC50= 0.19 μM).1,3 1.Hamano, K., Kinoshita-Okami, M., Minagawa, K., et al.Aquastatin A, an inhibitor of mammalian adenosine triphosphatases from Fusarium aquaeductuum. Taxonomy, fermentation, isolation, structure determination and biological propertiesJ. Antibiot. (Tokyo)46(11)1648-1657(1993) 2.Kwon, Y.-J., Fang, Y., Xu, G.-H., et al.Aquastatin A, a new inhibitor of enoyl-acyl carrier protein reductase from Sporothrix sp. FN611Biol. Pharm. Bull.32(12)2061-2064(2009) 3.Seo, C., Soh, J.H., Oh, H., et al.Isolation of the protein tyrosine phosphatase 1B inhibitory metabolite from the marine-derived fungus Cosmospora sp. SF-5060Bioorg. Med. Chem. Lett.19(21)6095-6097(2009) |
目录号 | 产品名/同用名 | 种属 | 表达系统 | ||
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TMPY-06067 | Influenza A H1N1 (A/Brisbane/02/2018) Neuraminidase/NA Protein (His) | H1N1 | Baculovirus Insect Cells | ||
Influenza A H1N1 (A/Brisbane/02/2018) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.3 kDa.
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TMPY-06066 | Influenza A H3N2 (A/Kansas/14/2017) Neuraminidase/NA Protein (His) | H3N2 | Baculovirus Insect Cells | ||
Influenza A H3N2 (A/Kansas/14/2017) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.6 kDa and the accession number is A0A2L2FIU4.
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TMPY-02344 | Influenza A H1N1 (A/California/04/2009) Neuraminidase/NA (His) | H1N1 | Baculovirus Insect Cells | ||
Influenza A H1N1 (A/California/04/2009) Neuraminidase/NA (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 50 kDa and the accession number is C3W5S3.
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TMPY-03845 | Influenza A H7N9 (A/Anhui/1/2013) Neuraminidase/NA Protein (His) | H7N9 | HEK293 Cells | ||
Influenza A H7N9 (A/Anhui/1/2013) Neuraminidase/NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.6 kDa.
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TMPY-02336 | Influenza A H3N2 (A/Babol/36/2005) Neuraminidase/NA Protein (His) | H3N2 | HEK293 Cells | ||
Influenza A H3N2 (A/Babol/36/2005) Neuraminidase/NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.6 kDa and the accession number is C0LU95.
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TMPY-05204 | Influenza A H1N1 (A/Michigan/45/2015) Neuraminidase/NA (His) | H1N1 | HEK293 Cells | ||
Influenza A H1N1 (A/Michigan/45/2015) Neuraminidase/NA (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.2 kDa.
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TMPY-04337 | Influenza A H1N1 (A/Puerto Rico/8/1934) Neuraminidase/NA Protein | H1N1 | HEK293 Cells | ||
Influenza A H1N1 (A/Puerto Rico/8/1934) Neuraminidase/NA Protein is expressed in HEK293 mammalian cells. The predicted molecular weight is 50.1 kDa and the accession number is P03468.2.
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TMPY-05205 | Influenza A H3N2 (A/Hong Kong/4801/2014) Neuraminidase/NA Protein (His) | H3N2 | HEK293 Cells | ||
Influenza A H3N2 (A/Hong Kong/4801/2014) Neuraminidase/NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.5 kDa.
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TMPY-00602 | Influenza A H3N2 (A/Aichi/2/1968) Neuraminidase/NA Protein (His) | H3N2 | HEK293 Cells | ||
Influenza A H3N2 (A/Aichi/2/1968) Neuraminidase/NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.8 kDa and the accession number is Q75VQ4.1.
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TMPY-06801 | Influenza A H1N1 (A/Wisconsin/67/2022) Neuraminidase/NA Protein (His) | H1N1 | Baculovirus Insect Cells | ||
Influenza A H1N1 (A/Wisconsin/67/2022) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.34 kDa.
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TMPY-06489 | Influenza A H3N2 (A/Darwin/9/2021) Neuraminidase/NA Protein (His) | H3N2 | Baculovirus Insect Cells | ||
Influenza A H3N2 (A/Darwin/9/2021) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 58.88 kDa.
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TMPY-06891 | Influenza A H1N1 (A/Sydney/5/2021) Neuraminidase/NA Protein (His) | H1N1 | Baculovirus Insect Cells | ||
Influenza A H1N1 (A/Sydney/5/2021) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.33 kDa.
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TMPY-06470 | Influenza A H3N2 (A/Hong Kong/2671/2019) Neuraminidase/NA Protein (His) | H3N2 | HEK293 Cells | ||
Influenza A H3N2 (A/Hong Kong/2671/2019) Neuraminidase/NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.08 kDa.
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TMPY-06852 | Influenza A H1N1 (A/California/07/2009) Neuraminidase/NA Protein (His) | H1N1 | Baculovirus Insect Cells | ||
Influenza A H1N1 (A/California/07/2009) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.28 kDa.
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TMPY-06446 | Influenza A H3N2 (A/England/42/1972) Neuraminidase/NA Protein (His) | H3N2 | Baculovirus Insect Cells | ||
Influenza A H3N2 (A/England/42/1972) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.78 kDa.
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TMPY-06799 | Influenza A H1N1 (A/Victoria/4897/2022) Neuraminidase/NA Protein (His) | H1N1 | Baculovirus Insect Cells | ||
Influenza A H1N1 (A/Victoria/4897/2022) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.39 kDa.
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TMPY-05926 | Influenza A H1N1 (A/AA/Marton/1943) Neuraminidase/NA (His) | H1N1 | HEK293 Cells | ||
Influenza A H1N1 (A/AA/Marton/1943) Neuraminidase/NA (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.1 kDa and the accession number is A4GBW9.
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TMPY-06163 | Influenza A H3N2 (A/Cambodia/e0826360/2020) Neuraminidase/NA Protein (His) | H3N2 | Baculovirus Insect Cells | ||
Influenza A H3N2 (A/Cambodia/e0826360/2020) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.7 kDa.
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TMPY-06889 | Influenza A H3N2 (A/Hong Kong/01/1968) Neuraminidase/NA Protein (His) | H3N2 | Baculovirus Insect Cells | ||
Influenza A H3N2 (A/Hong Kong/01/1968) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.82 kDa.
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TMPY-06517 | Influenza A H1N1 (A/swine/Canada/01093/2006) Neuraminidase/NA Protein (His) | H1N1 | Baculovirus Insect Cells | ||
Influenza A H1N1 (A/swine/Canada/01093/2006) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 53.64 kDa and the accession number is AKM14549.
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TMPY-00373 | Influenza A H7N7 (A/Netherlands/219/2003) Neuraminidase/NA Protein (His) | H7N7 | HEK293 Cells | ||
Influenza A H7N7 (A/Netherlands/219/2003) Neuraminidase/NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.6 kDa and the accession number is Q6VGI7.
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TMPY-06182 | Influenza A H3N2 (A/Singapore/INFIMH-16-0019/2016) Neuraminidase/NA Protein (His) | H3N2 | Baculovirus Insect Cells | ||
Influenza A H3N2 (A/Singapore/INFIMH-16-0019/2016) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.7 kDa.
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TMPY-00019 | Influenza A H10N8 (A/duck/Guangdong/E1/2012) Neuraminidase/NA Protein (His) | H10N8 | Baculovirus Insect Cells | ||
Influenza A H10N8 (A/duck/Guangdong/E1/2012) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 50.2 kDa and the accession number is I6PU08.
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TMPY-00143 | Influenza A H5N1 (A/Thailand/1(KAN-1)/2004) Neuraminidase/NA Protein (His), Biotinylated | H5N1 | HEK293 Cells | ||
Influenza A H5N1 (A/Thailand/1(KAN-1)/2004) Neuraminidase/NA Protein (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.6 kDa.
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TMPY-06162 | Influenza A H1N1 (A/Wisconsin/588/2019)/(A/Victoria/2570/2019) Neuraminidase/NA Protein (His) | H1N1 | Baculovirus Insect Cells | ||
Influenza A H1N1 (A/Wisconsin/588/2019)/(A/Victoria/2570/2019) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 54.3 kDa.
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TMPY-02528 | Influenza A H9N2 Neuraminidase/NA Protein | H9N2 | HEK293 Cells | ||
Influenza A H9N2 Neuraminidase/NA Protein is expressed in HEK293 mammalian cells.
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TMPY-02448 | Influenza A H3N2 Neuraminidase/NA Protein | H3N2 | HEK293 Cells | ||
Influenza A H3N2 Neuraminidase/NA Protein is expressed in HEK293 mammalian cells. The accession number is C0LU95.
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TMPY-02339 | Influenza A H3N2 Neuraminidase/NA Protein (R292K) | H3N2 | HEK293 Cells | ||
Influenza A H3N2 Neuraminidase/NA Protein (R292K) is expressed in HEK293 mammalian cells. The accession number is C0LU95.
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TMPY-02338 | Influenza A H3N2 Neuraminidase/NA Protein (N294S) | H3N2 | HEK293 Cells | ||
Influenza A H3N2 Neuraminidase/NA Protein (N294S) is expressed in HEK293 mammalian cells. The accession number is C0LU95.
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TMPY-02152 | Influenza A H5N1 Neuraminidase/NA Protein (H255Y) | H5N1 | HEK293 Cells | ||
Influenza A H5N1 Neuraminidase/NA Protein (H255Y) is expressed in HEK293 mammalian cells. The predicted molecular weight is 49.2 kDa and the accession number is A7Y9K2.
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TMPY-04185 | Influenza A H4N6 (A/mallard/Ohio/657/2002) Neuraminidase/NA Protein (His) | H4N6 | Baculovirus Insect Cells | ||
Influenza A H4N6 (A/mallard/Ohio/657/2002) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 50.2 kDa and the accession number is A4JYU4.
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TMPY-04338 | Influenza A H3N2 Neuraminidase/NA Protein (H274Y) | H3N2 | HEK293 Cells | ||
Influenza A H3N2 Neuraminidase/NA Protein (H274Y) is expressed in HEK293 mammalian cells. The accession number is C0LU95.
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TMPY-04048 | Influenza A H1N1 Neuraminidase/NA Protein (N295S) | H1N1 | HEK293 Cells | ||
Influenza A H1N1 Neuraminidase/NA Protein (N295S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 52 kDa and the accession number is C3W5S3.
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TMPY-02337 | Influenza A H3N2 Neuraminidase/NA Protein (E119V) | H3N2 | HEK293 Cells | ||
Influenza A H3N2 Neuraminidase/NA Protein (E119V) is expressed in HEK293 mammalian cells. The accession number is C0LU95.
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TMPY-02151 | Influenza A H1N1 Neuraminidase/NA Protein (H275Y) | H1N1 | HEK293 Cells | ||
Influenza A H1N1 Neuraminidase/NA Protein (H275Y) is expressed in HEK293 mammalian cells. The predicted molecular weight is 47.8 kDa and the accession number is C3W5S3.
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TMPY-03843 | Influenza A H7N9 (A/Shanghai/1/2013) Neuraminidase/NA Protein | H7N9 | HEK293 Cells | ||
Influenza A H7N9 (A/Shanghai/1/2013) Neuraminidase/NA Protein is expressed in HEK293 mammalian cells.
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TMPY-04849 | Influenza A H3N2 (A/Aichi/2/1968) Neuraminidase/NA Protein | H3N2 | HEK293 Cells | ||
Influenza A H3N2 (A/Aichi/2/1968) Neuraminidase/NA Protein is expressed in HEK293 mammalian cells. The predicted molecular weight is 52.2 kDa and the accession number is Q75VQ4.1.
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TMPY-04885 | Influenza B (B/PHUKET/3073/2013) Neuraminidase/NA Protein (His) | Influenza B | Baculovirus Insect Cells | ||
Influenza B (B/PHUKET/3073/2013) Neuraminidase/NA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 49.5 kDa.
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TMPY-05925 | Influenza A H1N1 (A/Henry/1936) Neuraminidase/NA (His) | H1N1 | HEK293 Cells | ||
Influenza A H1N1 (A/Henry/1936) Neuraminidase/NA (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.3 kDa and the accession number is A4GCI9.
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TMPY-05938 | Influenza A H3N2 (A/Albany/18/1968) Neuraminidase/NA Protein (His) | H3N2 | HEK293 Cells | ||
Influenza A H3N2 (A/Albany/18/1968) Neuraminidase/NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.8 kDa and the accession number is A4JZ31.
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TMPY-04532 | Influenza A H7N9 (A/Anhui/1/2013) Neuraminidase/NA Protein | H7N9 | HEK293 Cells | ||
Influenza A H7N9 (A/Anhui/1/2013) Neuraminidase/NA Protein is expressed in HEK293 mammalian cells.
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TMPY-05930 | Influenza A H1N1 (A/Auckland/6/1996) Neuraminidase/NA (His) | H1N1 | HEK293 Cells | ||
Influenza A H1N1 (A/Auckland/6/1996) Neuraminidase/NA (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.5 kDa and the accession number is A5JVE2.
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TMPY-05929 | Influenza A H1N1 (A/Beijing/262/1995) Neuraminidase/NA (His) | H1N1 | HEK293 Cells | ||
Influenza A H1N1 (A/Beijing/262/1995) Neuraminidase/NA (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.3 kDa and the accession number is B4UPG0.
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TMPY-05927 | Influenza A H1N1 (A/Baylor/11515/1982) Neuraminidase/NA (His) | H1N1 | HEK293 Cells | ||
Influenza A H1N1 (A/Baylor/11515/1982) Neuraminidase/NA (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.4 kDa and the accession number is Q1WP17.
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TMPY-00958 | Influenza A H1N1 (A/California/04/2009) Neuraminidase/NA (Fc) | H1N1 | HEK293 Cells | ||
Influenza A H1N1 (A/California/04/2009) Neuraminidase/NA (Fc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 76 kDa and the accession number is C3W5S3.
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TMPY-05757 | Influenza A H7N9 (A/Anhui/1/2013) Neuraminidase/NA Protein (His), Biotinylated | H7N9 | HEK293 Cells | ||
Influenza A H7N9 (A/Anhui/1/2013) Neuraminidase/NA Protein (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.6 kDa.
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TMPY-05942 | Influenza A H3N2 (A/Hong Kong/CUHK19579/1998) Neuraminidase/NA Protein (His) | H3N2 | HEK293 Cells | ||
Influenza A H3N2 (A/Hong Kong/CUHK19579/1998) Neuraminidase/NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.4 kDa and the accession number is B5ALX7.
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TMPY-05933 | Influenza A H1N1 (A/Arizona/13/2008) Neuraminidase/NA (His) | H1N1 | HEK293 Cells | ||
Influenza A H1N1 (A/Arizona/13/2008) Neuraminidase/NA (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.3 kDa and the accession number is B9W3K0.
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TMPY-04850 | Influenza A H1N1 (A/USSR/90/1977) Neuraminidase/NA Protein | H1N1 | HEK293 Cells | ||
Influenza A H1N1 (A/USSR/90/1977) Neuraminidase/NA Protein is expressed in HEK293 mammalian cells. The predicted molecular weight is 51.9 kDa and the accession number is P03469.2.
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TMPY-05931 | Influenza A H1N1 (A/Auckland/606/2001) Neuraminidase/NA (His) | H1N1 | HEK293 Cells | ||
Influenza A H1N1 (A/Auckland/606/2001) Neuraminidase/NA (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.2 kDa and the accession number is A6M7B6.
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